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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XDH All Species: 33.94
Human Site: S766 Identified Species: 74.67
UniProt: P47989 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47989 NP_000370.2 1333 146424 S766 G E M E L F V S T Q N T M K T
Chimpanzee Pan troglodytes XP_525729 1333 146376 S766 G E M E L F V S T Q N T M K T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540143 1333 147201 S767 G E L E L F A S T Q N T M K T
Cat Felis silvestris
Mouse Mus musculus Q00519 1335 146500 S768 G E M E L F V S T Q N T M K T
Rat Rattus norvegicus P22985 1331 146224 S765 G E M E L F V S T Q N T M K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509432 1297 142673 A754 F Q T H S C I A I P K G E E G
Chicken Gallus gallus P47990 1358 149595 S794 G E M E L F V S T Q N L M K T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688983 1351 148155 S787 G E M E L F V S T Q S A S K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10351 1335 146909 S770 D E L E L F C S T Q H P S E V
Honey Bee Apis mellifera XP_001119950 1356 152206 S794 D E L E I F C S T Q H P T E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7G192 1321 144562 S756 N C I V V Y S S T Q T P Q Y V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 90.4 N.A. 89.1 90.3 N.A. 70.4 72.3 N.A. 67.8 N.A. 52.6 52.4 N.A. N.A.
Protein Similarity: 100 99.6 N.A. 95.4 N.A. 95.1 95.8 N.A. 82.3 84 N.A. 81.4 N.A. 69.5 70.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 86.6 N.A. 100 100 N.A. 0 93.3 N.A. 80 N.A. 46.6 40 N.A. N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 26.6 93.3 N.A. 86.6 N.A. 66.6 66.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 52.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 10 0 0 0 10 0 0 0 % A
% Cys: 0 10 0 0 0 10 19 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 82 0 82 0 0 0 0 0 0 0 0 10 28 0 % E
% Phe: 10 0 0 0 0 82 0 0 0 0 0 0 0 0 0 % F
% Gly: 64 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 19 0 0 0 0 % H
% Ile: 0 0 10 0 10 0 10 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 64 0 % K
% Leu: 0 0 28 0 73 0 0 0 0 0 0 10 0 0 10 % L
% Met: 0 0 55 0 0 0 0 0 0 0 0 0 55 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 55 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 28 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 91 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 0 10 91 0 0 10 0 19 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 91 0 10 46 10 0 64 % T
% Val: 0 0 0 10 10 0 55 0 0 0 0 0 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _